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. 2006 Feb 10;124(3):459-61.
doi: 10.1016/j.cell.2006.01.022.

Rejuvenating exhausted T cells during chronic viral infection

Taku Okazaki  1 , Tasuku Honjo
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Rejuvenating exhausted T cells during chronic viral infection (VSports app下载)

"VSports最新版本" Taku Okazaki et al. Cell. .
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Abstract

In a recent paper in Nature, show that the immunoreceptor PD-1 is upregulated by "exhausted" T cells during the chronic phase of viral infection in mice. Remarkably, blocking the interaction between PD-1 and its ligand, PD-L1, reactivates these T cells and reduces viral load VSports手机版. .

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