Aim: To determine in critically ill patients the value of procalcitonin (PCT), C-reactive protein (CRP), sequential organ failure assessment (SOFA) score and white blood cell count in diagnosis and monitoring of sepsis VSports手机版. .

Methods: Patients admitted to a medicosurgical intensive care unit in a prospective, observational study, were observed consecutively V体育安卓版. According to ACCP/SCCM Consensus Conference definition were defined 4 groups: SEPSIS/SS (sepsis, severe sepsis, septic shock), SIRS, No-SIRS and TRAUMA. .

Results: Two hundred and fifty five clinical events on a total of 1 826 observation days were observed: 111 SEPSIS/SS, 49 TRAUMA, 45 SIRS and 50 No-SIRS. ROC values, in the diagnosis of sepsis, were 0. 88 for PCT, 0. 74 for CRP, 0. 8 for Sepsis score, 0. 74 for SOFA, 0. 62 for neu-throphils granulocytes (p<0. 05). The best cut-off values in the diagnosis of sepsis were 0. 47 ng/mL for PCT and 128 mg/L for CRP. PCT and SOFA were higher in septic shock than in severe sepsis and sepsis (p<0. 05 in all cases) V体育ios版. The maximum CRP level in SEPSIS/SS was reached only after 24-48 h of observation. Admission PCT value of TRAUMA patients whom evolving in septic complication was higher than patients with a favourable course: 3. 4 ng/mL (range 2. 63-12. 71) vs 1. 2 ng/mL (range 0. 5-5. 2) (p<0. 05). TRAUMA patients with septic complications present an early and quick significant increase of PCT (p<0. 05). .

Conclusions: PCT and CRP may be useful together with bacteriological data in sepsis diagnosis; PCT and SOFA closer correlate with the infection severity; PCT is the better parameter to estimate severity, prognosis or further course of the disease. VSports最新版本.