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Review
. 2005 Dec;7(11):477-85.
doi: 10.1007/BF02717000.

Double minutes, cytogenetic equivalents of gene amplification, in human neoplasia - a review (VSports手机版)

Erich Gebhart  1
Affiliations
Review

Double minutes, cytogenetic equivalents of gene amplification, in human neoplasia - a review

Erich Gebhart. Clin Transl Oncol. 2005 Dec.

Abstract

Double minutes are tiny spherical chromatin bodies of a few mega-base pairs of size which are found occasionally in hematopoietic neoplasia and more or less often in human solid tumors. They have been associated with worse prognosis and poor outcome of the malignancies where present VSports手机版. With the beginning era of molecular cytogenetics they could be defined as cytogenetic equivalents of amplified DNA sequences. The identification of involved chromosomal segments and their molecular nature led to the development of molecular genetic techniques for a rapid and reliable detection of prognostically important oncogene amplifications in human tumors and,as a consequence, to gene-targeted therapy. .

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"VSports在线直播" References

    1. Leuk Res. 1997 Aug;21(8):703-9 - "VSports最新版本" PubMed
    1. Eur J Cancer. 1995;31A(4):520-3 - PubMed
    1. Br J Haematol. 1995 Jun;90(2):486-8 - V体育2025版 - PubMed
    1. Cancer Genet Cytogenet. 2004 Nov;155(1):1-24 - V体育安卓版 - PubMed
    1. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11368-73 - PubMed

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