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Clinical Trial
. 2005 Jun;22(6):749-55.
doi: 10.1111/j.1464-5491.2005.01501.x.

Frequency and predictors of hypoglycaemia in Type 1 and insulin-treated Type 2 diabetes: a population-based study

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Clinical Trial

Frequency and predictors of hypoglycaemia in Type 1 and insulin-treated Type 2 diabetes: a population-based study

L A Donnelly et al. Diabet Med. 2005 Jun.

Abstract

Aims: To ascertain the frequency and identify predictors of self-reported hypoglycaemia in Type 1 and insulin-treated Type 2 diabetes. VSports手机版.

Methods: A random sample of 267 people with insulin-treated diabetes were recruited from a population-based diabetes register in Tayside, Scotland. Each subject prospectively recorded the number of mild and severe hypoglycaemic episodes experienced over a 1-month period. Ordinal logistic regression was performed to identify potential predictors of hypoglycaemia V体育安卓版. .

Results: Five hundred and seventy-two hypoglycaemic events were reported by 155 patients. The participants with Type 1 diabetes had a total of 336 hypoglycaemic events with a rate of 42. 89 events per patient per year. Of these, nine were severe hypoglycaemic events, with a rate of 1. 15 events per patient per year. Participants with insulin-treated Type 2 diabetes experienced a total of 236 hypoglycaemic events with a rate of 16. 37 events per patient per year. Of these, five were severe hypoglycaemic events, which would be equivalent to 0 V体育ios版. 35 events per patient per year. Predictors of hypoglycaemia in Type 1 diabetes were a history of previous hypoglycaemia (P = 0. 006) and co-prescribing of any oral drug (P = 0. 048). In patients with insulin-treated Type 2 diabetes, a history of previous hypoglycaemia (P < 0. 0001) and duration of insulin treatment (P = 0. 014) were significant predictors. .

Conclusion: The incidence of self-reported severe hypoglycaemia in insulin-treated Type 2 diabetes is lower than in Type 1 diabetes but does occur more often than previously reported and with sufficient frequency to cause significant morbidity VSports最新版本. Duration of insulin treatment is a key predictor of hypoglycaemia in insulin-treated Type 2 diabetes. .

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