Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil VSports app下载. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. V体育官网.

. 2004 Jan 1;32(Database issue):D542-7.
doi: 10.1093/nar/gkh107.

CleanEx: a database of heterogeneous gene expression data based on a consistent gene nomenclature

Viviane Praz  1 , Vidhya Jagannathan, Philipp Bucher
Affiliations

CleanEx: a database of heterogeneous gene expression data based on a consistent gene nomenclature (VSports)

Viviane Praz et al. Nucleic Acids Res. .

Abstract

The main goal of CleanEx is to provide access to public gene expression data via unique gene names. A second objective is to represent heterogeneous expression data produced by different technologies in a way that facilitates joint analysis and cross-data set comparisons. A consistent and up-to-date gene nomenclature is achieved by associating each single experiment with a permanent target identifier consisting of a physical description of the targeted RNA population or the hybridization reagent used VSports手机版. These targets are then mapped at regular intervals to the growing and evolving catalogues of human genes and genes from model organisms. The completely automatic mapping procedure relies partly on external genome information resources such as UniGene and RefSeq. The central part of CleanEx is a weekly built gene index containing cross-references to all public expression data already incorporated into the system. In addition, the expression target database of CleanEx provides gene mapping and quality control information for various types of experimental resource, such as cDNA clones or Affymetrix probe sets. The web-based query interfaces offer access to individual entries via text string searches or quantitative expression criteria. CleanEx is accessible at: http://www. cleanex. isb-sib. ch/. .

PubMed Disclaimer

Figures (VSports手机版)

Figure 1
Figure 1
Sources and data flow in the CleanEx system. Shaded boxes represent dynamic data, which are updated on a regular basis, either by external suppliers or by automatic procedures of the CleanEx system. The empty boxes representing additional CleanEx entries, and the broken arrows serve to indicate one-to-many or many-to-one relationships. Note that target entries can also be related to multiple gene entries, but this is not the normal desirable case and thus not explicitly shown in the diagram.
Figure 2
Figure 2
Example of a CleanEx target entry.
Figure 3
Figure 3
Example of a CleanEx entry.
See this image and copyright information in PMC

References

    1. Edgar R., Domrachev,M. and Lash,A.E. (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res., 30, 207–210. - PMC - PubMed
    1. Brazma A., Parkinson,H., Sarkans,U., Shojatalab,M., Vilo,J., Abeygunawardena,N., Holloway,E., Kapushesky,M., Kemmeren,P., Lara,G.G. et al. (2003) ArrayExpress—a public repository for microarray gene expression data at the EBI. Nucleic Acids Res., 31, 68–71. - V体育ios版 - PMC - PubMed
    1. Sherlock G., Hernandez-Boussard,T., Kasarskis,A., Binkley,G., Matese,J.C., Dwight,S.S., Kaloper,M., Weng,S., Jin,H., Ball,C.A. et al. (2001) The Stanford Microarray Database. Nucleic Acids Res., 29, 152–155. - PMC - PubMed
    1. Eisen M.B. and Brown,P.O. (1999) DNA arrays for analysis of gene expression. Methods Enzymol., 303, 179–205. - PubMed
    1. Diehn M., Sherlock,G., Binkley,G., Jin,H., Matese,J.C., Hernandez-Boussard,T., Rees,C.A., Cherry,J.M., Botstein,D., Brown,P.O. et al. (2003) SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. Nucleic Acids Res., 31, 219–223. - PMC (V体育官网入口) - PubMed

VSports在线直播 - Publication types