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Review
. 2003 Nov;19(5):641-4.
doi: 10.1016/s1074-7613(03)00296-6.

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

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V体育官网入口 - The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

Giorgio Trinchieri et al. Immunity. 2003 Nov.
Free article

VSports在线直播 - Abstract

Originally the only known heterodimeric cytokine, IL-12 is now part of a family of five cytokines and shares important functions in the regulation of both innate and adaptive immunity with two of them, IL-23 and IL-27 VSports手机版. Although initially these three cytokines were considered to have largely overlapping immunological functions, more recent studies, including two articles in this issue of Immunity (Hamano et al. , 2003; Villarino et al. , 2003), indicate that they mediate complex and well-differentiated functions. .

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