Skip to main page content (V体育2025版)
U.S. flag

An official website of the United States government

Dot gov

The . gov means it’s official. Federal government websites often end in . gov or . mil VSports app下载. Before sharing sensitive information, make sure you’re on a federal government site. .

Https

The site is secure V体育官网. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. .

Case Reports
. 2001 Jun-Jul;23(5):294-9.
doi: 10.1097/00043426-200106000-00012.

Vidarabine therapy for severe chronic active Epstein-Barr virus infection

H Kimura  1 , M Morita, I Tsuge, Y Hoshino, N Tanaka, Y Ito, T Morishima
Affiliations
Case Reports

Vidarabine therapy for severe chronic active Epstein-Barr virus infection

"V体育2025版" H Kimura et al. J Pediatr Hematol Oncol. 2001 Jun-Jul.

"V体育2025版" Abstract

Purpose: Severe chronic active Epstein-Barr virus infection (SCAEBV) is an intractable disease with a poor prognosis, and a definitive treatment has not been established VSports手机版. We administered vidarabine to patients with natural killer (NK) cell-type SCAEBV and evaluated clinical and virologic effects. .

Patients and methods: Four patients with SCAEBV were enrolled in this study. These patients had various symptoms, including fever, chronic hepatitis, hepatosplenomegaly, and hypersensitivity to mosquito bites. All patients had increased numbers of NK cells in their peripheral blood, and most of these were infected with EBV V体育安卓版. Viral load was measured by in situ hybridization and quantitative polymerase chain reaction (PCR). .

Results: The patients all responded to the therapy, and their symptoms improved V体育ios版. After the therapy, the number of NK cells in their peripheral blood decreased. In two patients who were closely monitored, the viral load measured by in situ hybridization and quantitative PCR decreased in parallel with the symptomatic improvement. After discontinuing this drug, the patient's symptoms returned and the Epstein-Barr virus load increased again. .

Conclusion: These results indicate that vidarabine therapy is a therapeutic choice to control SCAEBV, although its effect may be transient VSports最新版本. .

PubMed Disclaimer

Publication types

MeSH terms (VSports在线直播)

LinkOut - more resources