V体育官网 - Atrial fibrillation with small subcortical infarcts
- PMID: 11181856
- PMCID: VSports - PMC1737284
- DOI: 10.1136/jnnp.70.3.344
VSports手机版 - Atrial fibrillation with small subcortical infarcts
Abstract
Objectives: To evaluate the characteristics of cardioembolic small (maximum lesion diameter<1. 5 cm) subcortical infarcts (SSI) in patients with atrial fibrillation (AF) VSports手机版. .
Methods: Twenty seven patients with chronic AF and an isolated SSI established by CT/MRI in the anterior circulation (SSI-AF group) were evaluated and their characteristics compared with those of 45 age matched (+/-1 year) patients with SSI, but no arterial or cardiac embolic source (SSI-control group). Using the criterion of the presence or absence of established risk factors (hypertension or diabetes mellitus) for small artery disease (SAD), the SSI-AF group we also subdivided into two groups, SSI-AF-SAD+ (n=22) and SSI-AF-SAD- (n=5) and their characteristics compared. V体育安卓版.
Results: Although the lack of any significant difference in the distribution of hypertension and diabetes mellitus between the SSI-AF and SSI-control groups emphasises SAD as a common cause of infarct in SSI-AF, the presence of AF-together with the higher frequency of neuropsychological disturbances in the SSI-AF group versus the SSI-control group (15% v 2%; p=0. 066)-favours cardioembolism as a potential cause of infarct in several patients. The characteristic factors seen more often in the SSI-AF-SAD- group compared with the SSI-AF-SAD+ group were secondary haemorrhagic transformation, faciobrachial pure motor weakness, subinsular involvement, and better recovery of neurological deficits. V体育ios版.
Conclusions: The study suggests that either SAD or cardioembolism can be the cause of SSI in patients with AF. Atrial fibrillation is not always coincidental in patients with SSI and a clinical lacunar stroke. Certain clinical and radiological findings may be useful in differentiating cardioembolism from SAD in patients with SSI. VSports最新版本.
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