Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa
- PMID: 10629007
- DOI: "V体育安卓版" 10.1093/jac/45.1.9
"VSports最新版本" Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa
Abstract
Membrane vesicles were isolated from one beta-lactam-sensitive and three beta-lactam-resistant Pseudomonas aeruginosa clinical isolates from patients with cystic fibrosis. The presence of the chromosomally encoded beta-lactamase in the membrane vesicles was shown by electron microscopy and enzymatic studies. This is the first report of extracellular secretion of beta-lactamase in P. aeruginosa and it seems that the enzyme is packaged into membrane vesicles VSports手机版. .
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