These medications help manage symptoms of many mental health conditions, as well as certain physical health conditions. These medications often work well when paired with therapy VSports在线直播. SNRIs are usually well tolerated, with mild or minimal side effects.
Common side effects may include:
Each medication has different side effects V体育2025版. Ask your provider or pharmacist for more information about each type.
While these medications are generally safe, they may cause rare but serious complications in some cases:
If you’re thinking about suicide, you can reach out for help. Let your provider know. You can also call or text 988 (U.S.) to reach the Suicide and Crisis Lifeline. Someone is available to talk to you 24/7.
Some medications may interact with SNRIs, including:
This isn’t a complete list. Talk to your healthcare provider about all the medications and supplements you currently take. They’ll let you know if an SNRI is the safest option to manage your symptoms.
If you need surgery while taking an SNRI, tell your surgeon. These medications may change your blood pressure while you’re asleep and under anesthesia. Your provider may need to adjust your dose before the procedure. Never change or stop your medication unless your provider says it’s safe.
It’s best to avoid alcohol while taking antidepressants, including SNRIs. Alcohol is a depressant and might interfere with how well the medication works. It can sometimes make depression symptoms worse. If you have concerns about drinking, talk to your provider.
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SNRIs may also pose risks during pregnancy. Some studies show they can affect a developing fetus. But stopping treatment suddenly can be harmful, too, as untreated depression or anxiety may worsen. If you’re pregnant or planning to become pregnant, talk with your provider. They’ll go over the possible risks and benefits and help you choose the safest option.
If you need or want to stop taking an SNRI, your provider will help you gradually reduce your dose. Quitting abruptly can lead to a group of symptoms known as antidepressant discontinuation syndrome. These symptoms typically happen if you’ve been on the medication for six weeks or longer.
SNRIs take time to work. Most people start to notice benefits after four to six weeks at the right dose. For some, it may take nine to 12 weeks. If you don’t feel better by then, check in with your provider. They may suggest adjusting your treatment plan.
SNRIs (serotonin and norepinephrine reuptake inhibitors) are commonly prescribed, and for good reason. These medications can help with more than just depression, from easing nerve pain to managing anxiety or menopause symptoms. If you’re considering an SNRI or already taking one, know that your provider is your best resource. They can answer your questions, help with side effects and make sure the medicine is right for you.
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Last reviewed on 09/26/2025.
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