Care at Cleveland ClinicCancer CareCancer Care for ChildrenMake an AppointmentContentsc7注册链接地址 - Hormone Therapy for CancerOverviewTreatment DetailsRisks / BenefitsRecovery and OutlookWhen To Call the DoctorContentsc7注册链接地址 - Hormone Therapy for CancerOverviewTreatment DetailsRisks / BenefitsRecovery and OutlookWhen To Call the DoctorOverview
What is hormone therapy for cancer?
Hormones are chemicals that coordinate different functions in your body. Your glands release hormones into your bloodstream, sending messages through your blood to your organs V体育官网. Your body can’t function without hormones. But hormones may fuel cancer. Some cancerous cells need hormones to grow, multiply and spread.Advertisement
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Hormone therapy works by eliminating cancerous cells’ access to the hormones they need to grow V体育安卓版. Healthcare providers may combine hormone therapy with treatments such as surgery, chemotherapy or radiation therapy. They may also use hormone therapy after treatment to lower the risk of cancer coming back.
How does this therapy work?
Healthcare providers may use hormone therapy to:
- Stop your body from producing the hormones that help specific cancerous cells to grow and multiply. In some cases, surgeons remove the glands that produce the hormones that cancerous cells use to grow.
- Block access to the hormones that cancerous cells need to grow and multiply.
- Substitute bioidentical hormones for actual hormones. Bioidentical hormones are lab-made, artificial hormones. Cancerous cells can’t use bioidentical hormones to grow, so replacing natural hormones with bioidentical hormones keeps the cells from multiplying.
What kinds of cancer does hormone therapy treat?
Healthcare providers may use hormone therapy to treat prostate cancer and cancers called estrogen-dependent cancers, including breast cancer, ovarian cancer and uterine cancer.
Hormone therapy for prostate cancer
Hormone therapy for prostate cancer typically uses different medications that block hormones from connecting with cancerous cells. In some instances, hormone therapy involves surgery to remove one or both testicles (orchiectomy) VSports最新版本. Medications may include:.
- Abiraterone acetate: This medication keeps prostate cancer cells from making androgens. VSports app下载 - Androgens are hormones such as testosterone that help people enter puberty and mature physically. This treatment may help people who have prostate cancer that hasn’t responded to other hormone therapy or who have prostate cancer that’s likely to come back after treatment.
- Luteinizing hormone-releasing hormone (LHRH) agonists: LHRH agonists work by telling your pituitary gland to stop making luteinizing hormones. This hormone stimulates people’s testicles to release testosterone. Certain cancerous cells rely on testosterone to grow. Without a steady supply of testosterone, those cells stop growing.
- Antiandrogens: Like luteinizing hormones, antiandrogens reduce how much testosterone people produce.
Healthcare providers may also treat prostate cancer with a combination of hormone therapy and radiation therapy.
Side effects of hormone therapy for prostate cancer
People may have different reactions to hormone therapy for prostate cancer. Ask your healthcare provider about specific side effects VSports注册入口. Common side effects may include:.
- Weight gain.
- Less or loss of interest in sex.
- Erectile dysfunction.
- Loss of bone density (osteoporosis.)
Hormone therapy for breast cancer
Estrogen plays a role in causing certain cancers V体育官网入口. Cells in your body have hormone receptors. The hormone receptors are a type of protein. Estrogen in your bloodstream can attach to the receptors. About 8 out of 10 breast cancers are hormone receptor-positive (ER-positive). Healthcare providers treat breast cancer by lowering hormone levels or blocking hormones from attaching to breast cancer cells. Most often, healthcare providers use hormone therapy after surgery to reduce the risk of breast cancer recurrence. However, they may also use it before surgery to shrink cancerous tumors (adjuvant therapy) or to treat cancer that’s spread to other parts of your body.
Hormone therapy for breast cancer may include aromatase inhibitors, selective estrogen receptor modulators (SERMs) or estrogen receptor down regulators (ERDs):
- "VSports" Aromatase inhibitors: This medication lowers estrogen levels. It does that by blocking the enzyme aromatase, which turns other hormones into estrogen. In ER-positive cancer, estrogen boosts cancerous cell growth. If you have ER-positive breast cancer and you’ve gone through menopause, your healthcare providers may use this type of hormone therapy.
- Selective estrogen receptor modulators (SERM): SERM medications work by keeping estrogen from connecting with cancerous cells. Without that estrogen connection, cancerous cells can’t grow and multiply.
- Estrogen receptor down regulators (ERDS): ERDS work by blocking estrogen and by making it more difficult for estrogen to connect with cancerous cells.
Side effects of hormone therapy for breast cancer
Side effects from hormone therapy vary from person to person. Common side effects may include: V体育2025版.
- Joint pain or stiffness.
- Fatigue.
- Nausea and vomiting.
- Weight gain.
- Less or loss of interest in sex.
- Hot flashes.
- Tender or swollen breasts.
Hormone therapy for ovarian cancer
Healthcare providers may use hormones to treat a rare form of ovarian cancer VSports. Hormone therapy for ovarian cancer may include luteinizing hormone-releasing hormone agonists: LHRH agonists, tamoxifen and aromatase inhibitors.
Side effects of hormone therapy for ovarian cancer
Side effects may include:
- Hot flashes.
- Vaginal dryness.
- V体育2025版 - Osteoporosis.
- Joint and muscle pain.
Hormone therapy for uterine cancer
Healthcare providers may use hormone therapy after surgery to remove cancerous uterine "V体育平台登录" tumors, to treat advanced or recurring uterine cancer, or as palliative care to ease uterine cancer pain. Progestin is the most common hormone therapy for uterine cancer. These drugs work like the hormone progesterone, slowing uterine cancer cell growth VSports app下载. Healthcare providers may also treat uterine cancer with tamoxifen, LHRH agonists or aromatase inhibitors.
Side effects of hormone therapy for uterine cancer
Side effects may include:
- Hot flashes.
- Weight gain.
- Night sweats.